Increased Th2-like Invariant Natural Killer T cells in Peripheral Blood From Patients With Asthma

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Increased Th2-like Invariant Natural Killer T cells in Peripheral Blood From Patients With Asthma

PURPOSE Invariant natural killer T (iNKT) cells might play an important role in asthma pathogenesis in humans. Our previous study found no difference in the number of blood iNKT cells between asthma patients and controls. However, few studies have examined the function of blood iNKT cells in human asthma. METHODS Twenty asthma patients and eight controls were included in this study. Blood iNK...

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interleukin-12 and peripheral blood invariant natural killer t cells as an axis in childhood asthma pathogenesis

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Increased Natural Killer Cells Activity in Schizophrenic Patients

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Invariant Natural Killer T Cells

Invariant Natural killer T cell (iNKT cells) are a subset of T cells, which are narrowly defined as a T cell lineage expressing a semi-invariant CD1d-restricted T cell Receptors (TCRs) composed by Vα24-Jα18/Vβ11 in human, and Vα14-Jα18/Vβ8,Vβ7, and Vβ2 in mouse. Unlike conventional T cells which recognize peptides bound to highly polymorphic major histocompatibility complex (MHC) class I and II...

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ژورنال

عنوان ژورنال: Allergy, Asthma & Immunology Research

سال: 2014

ISSN: 2092-7355,2092-7363

DOI: 10.4168/aair.2014.6.5.444